Seagen

Principal Scientist Formulation

Technical Operations & Process Sciences - Bothell, Washington

Description

Seagen is a global, multi-product biotechnology company dedicated to developing and commercializing transformative cancer medicines. As the industry leader in antibody-drug conjugate (ADC) technology, we pioneered a new generation in the science of harnessing antibodies to deliver cell-killing agents directly to cancer cells. Seagen’s dedication to improving the lives of cancer patients goes beyond science, and we believe that every employee has a role in contributing to this mission. By working together with a shared dedication and diverse perspectives, we are able to reach our full potential and make a real difference in the world. Seagen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Put your passion to work at Seagen and join us!

Summary

A successful Senior/Principal Scientist & Technical Development Lead will enhance the long-term growth of Seagen’s development organization through innovation, collaboration, and scientific excellence, increasing our internal capabilities and improving operational efficiency to deliver transformative cancer therapies. This specific role is scoped to include leadership of technical development activities for a late-stage clinical asset at Seagen.

Requirements or Responsibilities:

• Lead technical development sub-team for early- and late-stage programs to define and execute CMC strategy
• Lead the development of robust liquid and lyophilized products for antibodies and antibody-drug conjugates (ADCs)
• Leverage literature, global regulatory guidance, and practical experience to complete deliverables and influence CMC strategies
• Recommend and implement new technology that advances knowledge and productivity within the department
• Identify and lead initiatives to increase capabilities, enhance process efficiency, or improve cross-functional operations
• Motivate and support the career development and technical growth of direct reports
• Author and review technical reports, manufacturing documents, and global regulatory submissions
• Present internally at department, project team, and governance, and externally at scientific conferences, industry groups, and workshops

Qualifications:

• 2+ years supervisory
• 5+ years of experience leading matrixed teams
• Hands-on experience and excellent understanding of analytical and biophysical protein characterization
• Excellent oral and written communication skills, ability to lead cross-functional development teams, and capability to provide strategic contributions
• Principal Scientist level requires broad subject matter expertise in multiple technical areas of formulation or DP process development and a working knowledge of both
• Demonstrated experience supporting regulatory submissions and a thorough understanding of ICH and global regulatory guidance

Education:

• S. or Ph.D. in Pharmaceutical Sciences, Biological Sciences, Biomedical or Chemical Engineering, Material Science, or a related discipline
• Principal Scientist level – Ph.D. with 5+ years of industry experience; M.S. with commensurate amount of industry experience
• Senior Scientist level – Ph.D. with 3+ years of industry experience; M.S. with commensurate amount of industry experience

As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit www.seagen.com.

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.

To prevent the spread of COVID-19, and as an integral part of its public health and safety measures, Seagen requires that all newly-hired employees be fully vaccinated against COVID-19 before commencing employment, subject to reasonable accommodation and other requirements of applicable federal, state, and local law.

Seagen

Seagen is an Equal Opportunity Employer

Submitted: 05/06/2022